The Eyes and Vision Outcomes Adjudication Project is one of the 9 adjudication projects developing methods for the long term follow up of the UK Biobank (UKB) Cohort, through centrally managed processes for ascertainment, confirmation, and sub-classification of both prevalent and incident outcomes (disease events) of interest. The principal means of follow-up will be through appropriate linkage of the UKB Cohort to a wide range of health care and other health-related records in the UK.
The group will consider the application and implications of this for eye health, to inform optimal approaches for case ascertainment and measurement over time in the absence of repeated phenotyping assessment. It represents the initial stages of the outcomes adjudication project that are necessary to inform the subsequent technical aspects of developing the processes for data linkage (and web-based applications for self-monitoring of visual health).
OBJECTIVES
• Confirm scope and priorities for Eyes and Vision Outcomes Adjudication
• Provide projections for expected prevalent and incident conditions in the UKB cohort
• Establish case definitions
• Review strengths and limitations of different approaches to case ascertainment
• Identify opportunities for integration of eyes and vision into the wider UK Biobank Outcomes Adjudication