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About UK Biobank
UK Biobank is a major national health resource, and a registered charity in its own right, with the aim of improving the prevention, diagnosis and treatment of a wide range of serious and life-threatening illnesses.
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Funding
The UK Biobank parent study was established by the Wellcome Trust medical charity, Medical Research Council, Department of Health, Scottish Government and the Northwest Regional Development Agency.
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What we do
- We use data from UK Biobank to study what causes eye disease and vision loss and investigate how these can be controlled and prevented
- Research into the causes of disease help to develop new, more effective treatments
Eye & vision data in UKBiobank
117,649 people took part in the eye and vision component of UK Biobank, undergoing modified logMAR visual acuity testing on a computerized system developed specifically for UK Biobank, autorefraction and keratometry (Tomey RC-5000), as well as measurement of intraocular pressure on a Reichert ORA Ocular Response Analyser, which returns measures of Goldmannequivalent intraocular pressure (IOP), corneal hysteresis, corneal resistance factor and IOP adjusted for corneal biomechanical properties. A smaller number (68,151) underwent simultaneous colour retinal photography, together with spectral domain optical coherence tomography (SD-OCT) in both eyes. These features, together with accompanying extensive phenotyping of all major organ systems, make the UK Biobank eye and vision dataset unique worldwide.
Research Groups
- Refractive Error
- Visual Acuity
- Intraocular Pressure
- Retinal Image Grading
- Retinal Vascular Morphometry
- Optical Coherence Tomography
- Giant Cell Arteritis & Polymyalgia
- Genetics
- Outcomes Adjudication & Record Linkage
- Cataract
- Crowdsourcing
- Retinal Detachment
- Retina & Cognition
- Nutrition & Eye
- Demyelination and Optic Neuritis